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Vildagliptin 維達列汀

規格: 95%
CAS: 274901-16-5
產品編號: H66251
MDL: MFCD09952339
品牌: INFI
Chemical Name(S)-1-[2-[(3-Hydroxyadamant-1-yl)amino]acetyl]pyrrolidine-2-carbonitrile
CAS Number274901-16-5
Synonym (2S)-
Chemical Name Translation(2S)-1-((3-羥基三環[3.3.1.1[3,7]]癸烷-1-基)氨基)乙酰基)吡咯烷-2-腈
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        Packing GroupIII
      • It is a new oral anti-hyperglycemic agent of a new dipeptidyl peptidase-IV (DPP-IV) inhibitor class of drugs. Antidiabetic.
      • {MCE} [2]. Wu YJ, et al. Dipeptidyl peptidase-4 inhibitor, vildagliptin, inhibits pancreatic beta cell apoptosis in associationwith its effects suppressing endoplasmic reticulum stress in db/db mice. Metabolism. 2015 Feb;64(2):226-35.
      • {TRC} Ahren, B., et al.: Diabetes Care, 27, 2874 (2004),
      • {TRC} Ahren, B., et al.: J. Clin. Endocrinol. Metab., 89, 2078 (2004),
      • {TRC} Barlocco, D., et al.: Curr. Opin. Invest. Drugs, 5, 1094 (2004),
      • {MCE} [1]. Villhauer EB, et al. 1-[[(3-hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine: a potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitor with antihyperglycemic properties. J Med Chem. 2003 Jun 19;46(13):2774-89.
      • {MCE} [1]. Villhauer EB, et al. 1-[[(3-hydroxy-1-adamantyl)amino]acetyl]-2-cyano-(S)-pyrrolidine: a potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitor with antihyperglycemic properties. J Med Chem. 2003 Jun 19;46(13):2774-89.
      • {MCE} [2]. Wu YJ, et al. Dipeptidyl peptidase-4 in
        • 274901-16-5 H66251 Vildagliptin 維達列汀
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        化學屬性

        Mol. FormulaC17H25N3O2
        Mol. Weight303
        Density1.27
        Boiling Point531.3

        *以上化合物性質及應用等信息僅供參考